Work

KRAS-G12C Inhibition–Induced Enrichment of MHC-Ihigh Immune-Active Tumor Cells Directs Immune-Effector TME Development to Augment Therapeutic Efficacy

Year: 2026

Type: article

Source: Cancer Immunology Research

DOI: 10.1158/2326-6066.cir-26-0213

Authors: Mohammed L. Ibrahim, Dana Foresman, Hong Zheng, Xiaoxian Liu, Mengyu Xie, Theresa A. Boyle, Joseph O. Johnson, Paulo C. Rodriguez, Daniel Abate-Daga, Brian Ruffell, Alexander R. Anderson, Eric B. Haura, Xiaoqing Yu, Amer A. Beg

Institutions: Cairo University, Moffitt Cancer Center

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Center for Cancer Research, National Cancer Institute

Awards: G7542604960, The Delta Ecology of NSCLC Treatment, Moffitt Cancer Center Support Grant, G9000925332

OpenAlex ID: W7212241727

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