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Oral Small-Molecule GLP-1 Receptor Agonists: Lessons from Clinical Candidates and a Blueprint for Next-Generation Design

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.6c00175
Authors: Jinrong Hu, Yunfei Zhang, Mengzhou Wang, Boxin Zhang, Bingxing Zhang, Changhua Ke, Chao Tang, Juan Xia, Qianqian Zhao, Hong Gao, Lei Tian, Chengyuan Liang
Institutions: Shaanxi University of Science and Technology, Guangdong Medical College
Language: English

Topic: Diabetes Treatment and Management
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Shaanxi Administration of Traditional Chinese Medicine, National Natural Science Foundation of China, Education Department of Shaanxi Province, Shaanxi Province Postdoctoral Science Foundation, Shaanxi Provincial Science and Technology Department
Awards: G1226090532, G1317970486, G1990859112, G2198868270, G3183402442, G3668690672, G3808809800, G4131783428, G4241336067, G4539827693, G4864270227, G5222274074, G576197809, G6178352047, G6256118587, G7641084792, G8151554990, G8742085759, G8861431676
OpenAlex ID: W7212246826
FWCI:
Cites: 114
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