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A combinatorial construct library enables an expanded expression range of secreted therapeutic proteins by probiotic yeast

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Year: 2026
Type: review
Source: Trends in biotechnology
DOI: 10.1016/j.tibtech.2026.08.012
Authors: Miranda J. Wallace, Christina Kratschmer, Brandon Brazil, Ilham Matiker, Esse M. Evbuomwan, Jerome Prusa, Jasmine Najari, Rehan Mehta, Ana Romani, Sophia Zhang, Jie Ning, Ryan A. Hagenson, James Liao, Bin Wang, Beth A. Helmink, Gautam Dantas
Institutions: Washington University in St. Louis, The University of Texas MD Anderson Cancer Center
Language: English

Topic: Fungal and yeast genetics research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: American Cancer Society, Washington University School of Medicine in St. Louis, National Human Genome Research Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Complementary and Integrative Health
Awards: G1234843147, G4918622355, Engineering yeast as a novel oral delivery vehicle for immunomodulatory cancer therapies., Expanding Opportunities in Genomic Research for Underrepresented Students, Clinical/Laboratory Training Academic Gastroenterology
OpenAlex ID: W7212252672
FWCI:
Cites: 45
Cited by:
Related to: 10
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