Work

Motor Improvements Following Non-Invasive Brain Stimulation with kTMP: A Case Study of Cerebellar Stroke

Year: 2026

Type: article

Abstract: Cerebellar ataxia results in debilitating impairments in balance, gait, and cognition, with no established effective treatments. Kilohertz transcranial magnetic perturbation (kTMP) is a novel subthreshold non-invasive brain stimulation (NIBS) method that delivers strong, subthreshold electric fields to the cerebellar cortex without discomfort. We present the case of a 78-year-old patient with cerebellar ataxia following hemorrhagic stroke who underwent amplitude-modulated kTMP (AM-kTMP) targeted to vermal and paravermal cerebellar regions. Active AM-kTMP produced improvements on clinical scales of ataxia alongside enhanced gait stability and cognitive performance, with no device-related adverse reactions, representing a promising NIBS intervention for cerebellar disorders.

Source: The Cerebellum

DOI: 10.1007/s12311-026-02078-z

Authors: Amanda Chirino-Pérez, Christina M. Merrick, Fredy Miranda-Casasola, Ludovica Labruna, Daniel Sheltraw, Richard B. Ivry

Institutions: University of California, Berkeley, Berkeley City College, Universidad Nacional Autónoma de México

Language: English

Topic: Transcranial Magnetic Stimulation Studies

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,790