Work

Targeting the HIV-1 NNRTI Entrance Channel: Structure-Guided Optimization for Enhanced Safety and Selectivity

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c02358

Authors: Yu-Jie Zhang, Ling Dong, Yu-Ting Niu, Zhen-Zhu Lei, Qian Xu, Limin Zhao, Hao Deng, Christophe Pannecouque, Erik De Clercq, Phuong-Thao Tran, Shuai Wang, Fen-Er Chen

Institutions: Fudan University, Zhengzhou University, Jiangxi Normal University, Rega Institute for Medical Research, KU Leuven, Hanoi University of Pharmacy

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Fudan University, National Key Research and Development Program of China

Awards: G1668341270, G5009013402, G5675847168

OpenAlex ID: W7212316003

FWCI:

Cites: 33

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