Relative efficacy, safety and immunogenicity of bivalent versus monovalent COVID-19 mRNA booster vaccines: a randomized trial
Year: 2026
Type: preprint
Study design: Clinical Trial
Source: Research Square
Authors: Sufia Dadabhai, Taraz Samandari, Bo Zhang, Aaron Hudson, Nonhlanhla Mkhize, Asa Tapley, Jessica Andriesen, Penny Moore, Zvavahera Chirenje, Peter Elyanu, Joseph Makhema, Ethel Kamuti, Harriet Nuwagaba-Biribonwoha, Jin Kee, Jiani Hu, Katekani Baloyi-Oseh, Parth Shah, Kentse Khuto, Maurine Miner, Richard Lessells, Sinethemba Bhebhe, Tandile Modise, Haajira Kaldine, Azwidihwi Takalani, Margaret Yacovone, John Hural, Leigh Fisher, Craig Magaret, Florence Aweyo, Sharlaa Badal-Faesen, William Brumskine, Soritha Coetzer, Rodney Dawson, Sinead Delany-Moretlwe, Katherine Gill, Mina Hosseinipour, Steve Innes, Priya Kassim, Emmanuel Kafulafula, Fatima Laher, Nelly Mandona, Moelo Malahleha, Vongane Maluleke, Matsontso Mathebula, Grace Mboya, Essack Mitha, Kathy Mngadi, Pamela Mda, Tumelo Moloantoa, Nivashnee Naicker, Vimla Naicker, Annet Nanvubya, Maphoshane Nchabeleng, Walter Otieno, Elsje Potgieter, Disebo Potloane, Zelda Punt, Jamil Said, Yashna Singh, Mohammed Tayob, Deo Wabwire, Myron Cohen, M. Juliana McElrath, Erica Andersen-Nissen, Guido Ferrari, James Kublin, Linda Gail-Bekker, Peter Gilbert, Nyaradzo Mgodi, Philip Kotze, Yunda Huang, Nigel Garrett, Glenda Gray, Lawrence Corey
Institutions: Johns Hopkins University, Texas A&M University, Fred Hutch Cancer Center, National Institute for Communicable Diseases, University of Washington, National Health Laboratory Service, University of Zimbabwe, Botswana Harvard AIDS Institute Partnership, Centre for Infectious Disease Research in Zambia, ICAP Global Health, University of KwaZulu-Natal, National Institute of Allergy and Infectious Diseases, Helen Joseph Hospital, Aurum Institute, University of Cape Town, University of the Witwatersrand, University of North Carolina at Chapel Hill, Soweto CTC, Newtown Hospital, Nelson Mandela Academic Hospital, Centre for the AIDS Programme of Research in South Africa, South African Medical Research Council, International AIDS Vaccine Initiative, Kenya Medical Research Institute, Acceleron Pharma (United States), Moi University, Desmond Tutu HIV Foundation, MUJHU Research Collaboration, Duke University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G1384187122, G172982731, G2276976381, G7522203623, G793395730, G819814859, HIV Vaccine Trials Network Laboratory Center, HIV Vaccines Clinical Trials Network Leadership and Operations Center, CoVPN 3008, Multi-Center, Randomized, Efficay Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern
OpenAlex ID: W7212934773