Work

Reviewer #2 (Public review): Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci

Year: 2026

Type: peer-review

Abstract: This important study presents an innovative combination of experimental evolution and CRISPR screening to study the genetic basis of a polygenic trait, resistance against octanoic acid in Drosophila.The evidence supporting the authors claims is solid.The work will be of interest to the Drosophila community and researchers interested in functional testing of polygenic traits.

Source: eLife

DOI: 10.7554/elife.111773.2.sa1

Language: English

Topic: Evolution and Genetic Dynamics

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W7213086422

Cites: 140

Cited by:

Related to: 10