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Supplementary Figure S1 from Epigenetic Liquid Biopsy Enables Universal Mutation-Agnostic Molecular Surveillance for High-Risk Neuroblastoma

Year: 2026

Type: supplementary-materials

Abstract: Supplementary Figure S1: Identification of neuroblastoma-specific DMRs through comparative methylome analysis to normal human cell-type atlas. Total of 152 neuroblastoma DMRs were identified in comparison to all tissue types in the human reference atlas (13). Given that neuroblastoma arises from neural crest cells, the analysis was repeated with neuronal cell types excluded from the atlas resulting in the identification of additional 36 “neuronal” regions.

DOI: 10.1158/1078-0432.33776359

Authors: Nurit Gal-Mark, Assaf Grunwald, Valid Gahramanov, Michal Hameiri-Grossman, Elena Shinderman-Maman, Dafna Gaas, Keren Shichrur, Jacques Mordoukh, Nino Oniashvili, Eva Chausky Barzakh, Aviv Sever, Shirah Amar, Shifra Ash, Yehudit Birger, Shai Izraeli, Yuval Ebenstein, Esther R. Berko

Language: English

Topic: Neuroblastoma Research and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7213232468

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