Figure S3 from PARG Governs a PARylation–Ubiquitination Toggle that Stabilizes RAD51AP1 to Drive Homologous Recombination–Mediated Chemoresistance
Year: 2026
Type: other
Abstract: Fig. S3 confirms that combining PARG inhibitor with 5-FU does not cause significant body weight loss or major organ toxicity in PDX models.
Authors: Hanyi He, Yangchan Hu, Ye Lu, Mingcong Deng, Qimei Bao, Dan Zu, Yuke Zhong, Chunkai Zhang, Chenlong You, Xiaohan Du, Siqi Liu, Yanhua He, Min Liu, Liangliang Gao, Xiangzheng Gao, Haidong Liu, Yixing Huang, Yiguan Chen, Dade Rong, John A. Tainer, Ji Jing, Yin Shi, Han-Ming Shen, Zu Ye, Xiangdong Cheng
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7213241418