Work

Pharmacological lipid-lowering therapies for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia: a systematic review and network meta-analysis

Year: 2026

Type: review

Abstract: OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: Primary To compare the effects and safety of lipid-lowering therapies, including statin regimens (high intensity, moderate intensity, and low intensity), non-statin therapies, and combination regimens, for the primary and secondary prevention of cardiovascular disease in adults, using pairwise and network meta-analysis where appropriate. Secondary To obtain an estimate of the relative ranking of these lipid-lowering therapies compared to placebo/no treatment.

Source: Cochrane Database of Systematic Reviews

DOI: 10.1002/14651858.cd016387