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Pediatric Medulloblastoma with Postoperative Complications and an Incidental Optic Pathway Glioma: A Case Report

Year: 2026

Type: article

Abstract: We report the case of a 14-year-old boy diagnosed with a posterior fossa medulloblastoma who exhibited progressive neurological symptoms. Preoperative MRI revealed a large, well-defined lesion centered at the fourth ventricle with both superior and inferior extensions. Surgical resection confirmed WHO Grade IV medulloblastoma on histopathology. Postoperatively, the patient developed complications, and follow-up imaging revealed a residual lesion as well as a new, incidental optic chiasmal mass consistent with an optic pathway glioma. The patient was planned for craniospinal irradiation (CSI) using 36 Gy in 20 fractions with concurrent vincristine chemotherapy, and a 10-fraction boost (18 Gy) to both medulloblastoma and optic glioma. This case highlights the importance of vigilant postoperative imaging, recognition of secondary pathologies, and a multidisciplinary treatment approach in pediatric neuro-oncology.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22767855

Authors: Fatima Mahmood, Sadia Sadiq, Usama Javed, Samina Siddique, Faieqa Aslam

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7213293473

FWCI:

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