RSM01, an extended half-life RSV monoclonal antibody with a high barrier to in vitro resistance
Year: 2026
Type: article
Abstract: Files regarding data sources and analyses performed to unveil the resistance barrier of the LMIC-focused candidate RSM01 relative to existing RSV mAbs by characterizing in vitro–selected escape mutants, their effects on viral fitness, the prevalence of associated mutations in circulating RSV sequences, and the susceptibility of contemporary global strains to RSM01. The results will be communicated in the paper entitled: "RSM01, an extended half-life RSV monoclonal antibody with a high barrier to in vitro resistance"
Source: Nature Communications
Authors: Terstappen, Jonne, Gustani-Buss, Emanuele C., Simonich, Cassandra A.L., McLellan, Jason S., Baillie, Vicky-Lynne, Bloom, Jesse D., Bont, Louis J., Caballero, Mauricio T., Chappin, Klasina, van Duijn, Janissa J.A., Juviler, Gavin, Lebbink, Robert Jan, van Lotringen, Isabelle C.E., Roggekamp, Joris J.T., Versnel, Anouk, Viveen, Marco C., van Zoggel, Hanneke J.A.A., Delemarre, Eveline M., Bonavia, Aurelio, Mazur, Natalie I.
Institutions: University Medical Center Utrecht, Wilhelmina Children's Hospital, Rega Institute for Medical Research, KU Leuven, Fred Hutch Cancer Center, The University of Texas at Austin, University of the Witwatersrand, Howard Hughes Medical Institute, Consejo Nacional de Investigaciones Científicas y Técnicas, National University of General San Martín
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $6,990
OpenAlex ID: W7213355600