Work

Mixed thiolate/alkoxide antimony cages for stable reversed-bilayer vesicle self-assembly

Year: 2026

Type: preprint

Abstract: A new two-step synthesis produces moisture-stable antimony and arsenic dithiothreitol cages. Structural analysis reveals that the Sb compounds self-assemble into reversed bilayers, consistent with pnictogen-bonded vesicle formation in organic media. The Sb assemblies more efficiently encapsulate and protect rhodamine B than the arsenic analogue or a topological mimic that lacks pnictogen-bonding capability. This work provides a synthetically accessible tool for partitioning organic media to allow for orthogonal reactivity.

Source: ChemRxiv

DOI: 10.26434/chemrxiv.15005281/v2

Authors: Lina M. Delgado, Olivia H. Villanueva, Shiva Moaven, Daniel K. Unruh, Dimitri Pappas, Anthony F. Cozzolino

Institution: Texas Tech University

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, Division of Chemistry

Awards: CAREER: Pnictogen Bonding in Solution: Developing Tools for the Self-assembly of Inverted Bilayer Membranes, Heteromolecular Dyads and Supramolecular Catalysts., G3314593163, G432733853, Acquisition of a 400 MHz NMR Spectrometer for Research and Education in Synthetic Chemistry, G6577711430

OpenAlex ID: W7213449051

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