Work

Suprachoroidal hemorrhage and detachment in the non-laser photocoagulation posterior pole after intravitreal Anti-VEGF injection: A case report

Year: 2026

Type: article

Abstract: Intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections are widely used for diabetic macular edema (DME) and neovascular ocular diseases. Suprachoroidal hemorrhage and detachment (SCHD) in the posterior pole non-laser photocoagulation area is an extremely rare complication after anti-VEGF injection, with no standardized management. We report a 56-year-old male with a 20-year history of type 2 diabetes, bilateral proliferative diabetic retinopathy (DR), neovascular glaucoma (NVG), and prior pars plana vitrectomy who developed SCHD in the right eye after intravitreal Conbercept injection. He was treated with retrobulbar triamcinolone acetonide injection. During follow-up, SCHD resolved completely with significant improvement in best-corrected visual acuity and stable intraocular pressure. Pathogenesis may involve low intraocular pressure, anti-VEGF-related vascular effects, diabetic vascular fragility, and chronic high intraocular pressure injury. Retrobulbar triamcinolone acetonide injection may represent a promising treatment option for this complication, although further evidence is needed to establish its efficacy. Strict perioperative blood glucose and intraocular pressure control, standardized injection technique, and close postoperative monitoring may be beneficial for high-risk patients.

Source: Therapeutic Advances in Ophthalmology

DOI: 10.1177/25158414261491534

Authors: Yikeng Huang, Jisen Tang, Chunyao Xie, Xionggao Huang

Institutions: Shanghai Jiao Tong University, Shanghai First People's Hospital, Hainan Medical University

Language: English

Topic: Retinal Diseases and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,650