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Genome Sequence of Human Cytomegalovirus Ig-KG-H2, a Variant of Strain KG Propagated in the Presence of Neutralizing Antibodies

Year: 2026

Type: article

Abstract: Human cytomegalovirus shed in infant urine was isolated and serially passaged in fibroblasts in the presence or absence of neutralizing antibodies. Comparison of the genome sequences of representative viruses Ig-KG-H2 (passed with antibody) and ϕ-KG-B5 (passed without antibody) revealed the presence of several mutations in each virus.

Source: UNC Libraries

DOI: 10.17615/1jgy-2m91

Authors: Hertel, Laura, Camiolo, Salvatore, Al Qaffas, Ahmed, McVoy, Michael A., Dittmer, Dirk P., Cui, Xiaohong, Schleiss, Mark R., Ourahmane, Amine, Davison, Andrew J., Nichols, Jenna

Institution: University of North Carolina at Chapel Hill

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: March of Dimes Foundation, Wellcome Trust, National Institute of Allergy and Infectious Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development

OpenAlex ID: W7213614934

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