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Antibacterial-activity, cytotoxicity, and physiochemical properties of tolfenpyrad analogs.

Year: 2026

Type: dataset

Abstract: Analogs of the tolfenpyrad scaffold were synthesized through the functionalization of pyrazole-5-carboxamide and p-methylphenoxybenzyloxy moieties by employing two established reaction schemes to derivatize the left side (LS) and right side (RS) of tolfenpyrad. The resultant set of 262 closely-related analogs represents an array of physicochemical properties with substitutions on the LS, RS, and in the middle region (MR) of the tolfenpyrad scaffold

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22862582

Authors: Eshraghi, Aria, Khalid, Nimra

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W7213770544

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