Work

Breast cancer-related lymphoedema: approach and management

Year: 2026

Type: article

Abstract: Lymphoedema is defined as the chronic progressive build-up of lymph fluid in interstitial tissues due to impaired drainage or obstruction within the lymphatic system.Lymph is rich in proteins, immune cells, lipids and metabolic waste.Chronic accumulation of lymph in interstitial tissues results in chronic inflammation, tissue fibrosis and remodelling.[1] Lymphoedema is mainly classified based on underlying aetiology as either primary or secondary.Primary lymphoedema results from congenital or genetic abnormalities in the development of the lymphatic drainage system.Secondary lymphoedema results from surgery, radiation therapy, infection, trauma or malignancy around the affected region.

Source: Singapore Medical Journal

DOI: 10.4103/singaporemedj.smj-2026-162

Authors: Llewelyn Yi Chang Tan, Matthew Rong Jie Tay, Ishwarpal Singh Grewal, Chin Jung Wong

Institutions: Tan Tock Seng Hospital, Singapore Cancer Society, Khoo Teck Puat Hospital

Language: English

Topic: Lymphatic System and Diseases

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7213976779