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Age- and sex-specific patterns in the prevalence of metabolic syndrome components in the Republic of Korea, 2014–2023: a repeated cross-sectional study of national health screening statistics

Year: 2026
Type: article
Study design: Observational Study
Abstract: Conflict of interestNo potential conflict of interest relevant to this article was reported.important risk factor for atherosclerosis, are critical for lowering the incidence and mortality of CAD and cerebral infarction.To promote appropriate treatment of dyslipidemia, the Korean Society of Lipid and Atherosclerosis (KSoLA) published the first guidelines for the management of hyperlipidemia in 1996, the second guideline in 2003, the second revision in 2009, and the third guidelines for treatment of dyslipidemia with added contents in 2015, in collaboration with 18 other relevant academic societies and organizations.5 However, new guidelines were published in Europe in 2016 and in the United States in 2017 based on new study findings, and new drugs, such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have been launched.[6][7][8] Therefore, the KSoLA Treatment Guideline Committee developed the fourth guidelines for treatment and management of dyslipidemia specific to Koreans based on evidence and expert opinions on the dynamically changing treatment modalities for dyslipidemia.The fourth guideline consists of information about the epidemiology of dyslipidemia, diagnosis and treatment criteria, lifestyle interventions, drug therapy, and dyslipidemia in specific patient groups.Finally, we present currently available data and the need to develop and validate scales to assess the risk of CVD specific to Koreans and CVD biomarkers appropriate for the Korean population.The level of evidence and strength of recommendations used in the fourth guideline are shown in Table 1.The fourth guideline is available in full text and an abstract form including tables and figures in Korean.This paper is an English summary of the full text.We hope the fourth guidelines for the treatment of dyslipidemia will be useful for health professionals treating dyslipidemia. EPIDEMIOLOGY OF DYSLIPIDEMIA IN KOREANS Cardiovascular disease in KoreansCVD is the leading cause of deaths worldwide, with an estimated 17 million people dying from CVD every year.1,2 In South Korea, the death rate resulting from diseases of the circulatory system was 187 men per 100,000 population and 145 women per 100,000 population in 1983 and 111 men per 100,000 population and 125 women per 100,000 in 2016, indicating little change over the years.However, the age-adjusted mortality rate, which excludes the influence of aging of the population during this period, decreased to about one-fifth of the initial rate (Fig. 1).Death from CAD has consistently increased since 1983, when the cause of death statistics were first measured, reaching 31 men per 100,000 and 26 women per 100,000 in 2016.However, age-adjusted mortality of CAD reached a peak in the early and mid-2000s and began to decline since then (Fig. 2).Deaths from cerebrovascular disease declined since 2000s, reaching 44 men per 100,000 and 47 women per 100,000 in 2016.Age-adjusted mortality for cerebrovascular disease has declined very quickly (Fig. 3).Among various cerebrovascular diseases, there were more deaths from cerebral hemorrhage (non-traumatic intracerebral hemorrhage and subarachnoid hemorrhage) until 2002, but deaths from cerebral infarction (ischemic stroke) have become more common since then.This is speculated to be due to the marked decline in the incidence and improved treatment outcomes of cerebral hemorrhage as a result of advances in treatment for hypertension.9 The prevalence and incidence of CVD are not accurately known due to a lack of nationwide statistics.Based on a review of various studies, however, the prevalence of CVD is rising 79
DOI: 10.24171/j.phrp.2026.0195
Institution: Inje University
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W7214009045
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