Work

Management of Bullous Pemphigoid and Norwegian Scabies with Dupilumab Plus Ivermectin

Year: 2026

Type: article

Abstract: Bullous pemphigoid is a severe autoimmune blistering disease, and Norwegian scabies is a rare comorbidity. However, conventional treatment methods, such as systemic corticosteroids, carry a high risk in the treatment of elderly patients. Herein, this rare comorbidity is described in an elderly patient. After an initial induction treatment with a low-to-moderate dose of corticosteroid, this patient achieved complete remission with a combination therapy of dupilumab (a monoclonal antibody targeting the interleukin-4/13 signaling pathway) and ivermectin. Therefore, the successful treatment of this rare case provides a promising strategy for reducing reliance on corticosteroids in high-risk populations.

Source: American Journal of Tropical Medicine and Hygiene

DOI: 10.4269/ajtmh.26-0186

Authors: Yanli Zhang, Yuting Liu, Hengan Yi