Child’s daily life at 10 years following moderate, late preterm, or early term birth: results from EPIPAGE-2 and ELFE cohorts
Year: 2026
Type: article
Study design: Observational Study
Abstract: Introduction Preterm birth includes four subgroups: extremely (<28 weeks’ gestation), very (28 +0 –31 +6 ), moderate (32 +0 –33 +6 , MPT) and late (34 +0 –36 +6 , LPT). While school attainment is well-studied across subgroups, other aspects of daily life are rarely reported for MPT, LPT and early term (37 +0 –38 +6 , ET) or are explored only qualitatively. Objective Assess daily life, including school and quality of life at age 10 years for MPT, LPT and ET compared with full-term (39 +0 -40 +6 , FT) peers. Methods Children born in 2011 from two birth cohorts (ELFE: ≥33 +0 weeks; EPIPAGE-2: ≤34 +6 weeks) completed a 10-year follow-up via telephone interview (n=8373) and home visit (n=6418). Weighting addressed selection bias. Outcome-wide regressions (modified Poisson, linear) were used to calculate adjusted relative risks (aRR) and beta-coefficients (β). Results MPT had a higher risk of receiving any school support (aRR 1.67, 95% CI 1.10 to 2.54). Their risk for difficulties in French and mathematics was, respectively, 1.32 (95% CI 1.01 to 1.74) and 1.50 (95% CI 1.13 to 1.99) times higher, while school-related quality of life was 0.30 (95% CI −0.58 to −0.02) SD lower relative to FT. They were 2.02 times more likely to be non-swimmers (95% CI 1.24 to 3.29). Both MPT/LPT were less likely to eat school meals but reported higher overall well-being scores (+0.16 SD and +0.13 SD, respectively). The study sample may under-represent socioeconomically deprived groups. Conclusions MPT/LPT children’s daily lives differ from those of FT children in some respects. Those discrepancies should be explored further to better understand needs and accommodate them. Findings may not generalise to disadvantaged groups.
Institutions: Inserm, Université Paris Cité, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université Sorbonne Paris Nord, Centre de Recherche Épidémiologie et Statistique, Université de Tours, Hôpital Bretonneau, Hôpital Intercommunal de Créteil, Centre Hospitalier Universitaire de Rouen, Institut national d'études démographiques, Institut national supérieur de formation et de recherche pour l'éducation inclusive, GRHAPES – Groupe de recherche sur le handicap, l'accessibilité, les pratiques éducatives et scolaires (UR 7287)
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funders: Equipex, Fondation PremUP, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Fondation pour la Recherche Médicale, Fondation de France, Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche, Socialdepartementet, Etablissement Français du Sang, Caisse nationale de solidarité pour l'autonomie
OpenAlex ID: W7214112870
