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Anticoagulation Dilemma in a Patient With Pulmonary Embolism and Massive Haemoptysis

Year: 2026

Type: article

Abstract: The development of worsening haemoptysis in a patient with pulmonary embolism presents a significant treatment challenge, especially in a low-resource setting where advanced interventions such as bronchial artery embolization may not be readily available. We present the case of a 40-year-old morbidly obese woman who was transferred to our facility with recurrent lower-limb deep vein thrombosis and a new diagnosis of bilateral pulmonary embolism. Following initiation of oral anticoagulation with apixaban, she developed worsening haemoptysis that persisted despite dose adjustments. She was subsequently stabilized and discharged on a vitamin K antagonist (warfarin). This case highlights the clinical challenges encountered in managing anticoagulation in the setting of significant bleeding and underscores the importance of individualized anticoagulation therapies.

Source: Cureus

DOI: 10.7759/cureus.116889

Authors: Isaac Mugwano, Faith Atim Emilly, Isaac Ssinabulya, David Salama Kaishusha, Joanita Nalyazi

Institution: Uganda Heart Institute

Language: English

Topic: Venous Thromboembolism Diagnosis and Management

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7214354150