Associated Factors of In-hospital Mortality in Adult Burn Patients: A Five-Year Retrospective Study.
Year: 2026
Type: article
Study design: Observational Study
Abstract: Introduction: Although comorbidities are recognized as important prognostic factors in burn patients, the impact of individual comorbidities and associated trauma on treatment outcomes has not been fully elucidated. This study aimed to evaluate the associations between individual comorbidities, the presence of comorbidities, associated trauma, and treatment outcomes in adult burn patients. Methods: A retrospective cohort study was conducted among all eligible adult burn patients (aged ≥18 years) admitted to Le Huu Trac National Burn Hospital, Vietnam, between January 2021 and December 2025. The primary outcome was in-hospital mortality. Demographic characteristics, burn characteristics, comorbidities, and associated trauma were extracted from the electronic medical records. Univariate and multivariate regression analyses were performed to identify factors independently associated with the study outcomes. Results: The study included 6653 adult burn patients with median age of 40 (interquartile range (IQR): 31 - 52) years (73.94% male). Among adult burn patients, hypertension and diabetes mellitus were the most common comorbidities (3.01% and 2.80%, respectively). The presence of comorbidities was an independent predictor of both complications and mortality (odds ratio (OR) = 1.926, 95% confidence interval (CI): 1.180-3.144, p = 0.009; and OR = 1.785, 95% CI: 1.057-3.014, p = 0.030, respectively), along with age, total burn size, full-thickness burn size, and inhalation injury (all p < 0.001). Chronic pulmonary disease (OR = 11.371, 95% CI: 2.972-43.498, p < 0.001) and paralysis (OR = 3.451, 95% CI: 1.085-10.976, p = 0.036) remained independent predictors of mortality. Associated trauma was independently associated with prolonged hospital stay (p = 0.033). Conclusions: Comorbidities were independently associated with both complications and mortality in adult burn patients. Chronic pulmonary disease and paralysis were identified as independent prognostic factors for mortality. Although associated trauma was not independently associated with mortality, it was independently associated with a prolonged hospital stay.
Institution: Vietnam Military Medical University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7214358594