Work

A Two-Step Synthesis of Covalent Genetically Encoded Libraries of Peptide-Derived Macrocycles Enables the Use of Electrophiles with Diverse Reactivity

Year: 2026

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.6c12299

Authors: James H. Walker, Arunika I. Ekanayake, Nichole Pedowitz, Ryan Qiu, Peter Girnt, Brett M. Babin, Alexey Atrazhev, Richard Long, Lela Vukovic, Olivier Julien, Matthew Bogyo, Ratmir Derda

Institutions: University of Alberta, Stanford Medicine, Stanford University, The University of Texas at El Paso

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Canada Foundation for Innovation, National Institute of Biomedical Imaging and Bioengineering

Awards: G3032813834, G364392047, G6814866464, G8866166386

OpenAlex ID: W7214424388

FWCI:

Cites: 52

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