CST1 Regulates ER-Mitochondrial Mg²⁺ Balance via MAGT1 to Promote Breast Cancer Metabolism and Growth
Year: 2026
Type: article
Abstract: . Our study unveils a non-canonical role for a secreted protein in regulating inter-organelle ion homeostasis to drive cancer metabolism and growth, and proposes a targeted peptide-based strategy for treating breast cancer.
DOI: 10.7150/ijbs.136015
Institutions: Kunming Institute of Zoology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Kunming Medical University, The Affiliated Yongchuan Hospital of Chongqing Medical University, Peking University Cancer Hospital, First Hospital of China Medical University, Wuhan Union Hospital, Huazhong University of Science and Technology
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,337
OpenAlex ID: W7214620996