Work

Lipid nanoparticles optimized for large RNA cargo and tissue targeting enhance in vivo genome editing

Year: 2026

Type: article

Source: Nature Biotechnology

DOI: 10.1038/s41587-026-03298-8

Authors: Songtao Dong, Fanglin Gong, Tyler Thomson, Yunshu Cai, Lauren Healy, Rick X. Z. Lu, Ziyu Zhou, Yue Xu, Jingan Chen, Margarita Savguira, Xianglei Fu, Sijin Luozhong, Muye Zhou, Payton Kirtley, Brandon K. Wilder, Bowen Li

Institutions: University of Toronto, Oregon Health & Science University, Vaccine and Gene Therapy Institute, University Health Network, Princess Margaret Cancer Centre

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7214659674

FWCI: 1.46

Cites: 75

Cited by: 1

Related to: 10