Work

Covalent-Allosteric Akt Inhibitors: Targeting Akt3 through Molecular Hybridization and Expanding the Isoform-Selective Toolbox

Year: 2026

Type: article

Source: ACS Chemical Biology

DOI: 10.1021/acschembio.6c00415

Authors: Kosmas Alexandros Pervanidis, Giovanni Danilo D’Angelo, Ioannis Athanasiadis, Hannah Jantzen, Andrea Scrima, Katharina Schäfer, Lena Quambusch, Matthias P. Müller, Daniel Rauh

Institution: TU Dortmund University

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

OpenAlex ID: W7214703022

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Cites: 32

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