Work

Subependymal Giant Cell Astrocytoma Mimicking Recurrent Ependymoma: Imaging Clues to the Diagnosis of Tuberous Sclerosis Complex

Year: 2026

Type: article

Abstract: Tuberous sclerosis complex (TSC), also known as Bourneville disease, is a multisystem genetic disorder that can involve the central nervous system. We report the case of an adolescent with a history of intraventricular ependymoma resection during childhood and ventriculoperitoneal shunt placement who presented with symptoms of intracranial hypertension. Brain imaging revealed a right intraventricular solid-cystic mass involving the foramen of Monro, associated with subependymal nodules and cortical tubers, suggesting previously undiagnosed TSC. This case emphasizes the importance of recognizing imaging features of TSC in patients presenting with intraventricular tumors to ensure accurate diagnosis and appropriate management.

Source: Cureus

DOI: 10.7759/cureus.117140

Authors: Abdelilah Bouymajjan, Asmae Oulad Amar, El Mahdi Choukri, Ali Meqor, Siham Alaoui Rachidi

Institution: Abdelmalek Essaâdi University

Language: English

Topic: Tuberous Sclerosis Complex Research

Subfield: Genetics (clinical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7214723077