Work

Rapid in vivo screening of tumor-targeting aptamers using zebrafish larvae

Year: 2026

Type: article

Abstract: approach can also assess off-target binding to healthy tissues without the time and cost associated with rodent models.

Source: Molecular Therapy — Nucleic Acids

DOI: 10.1016/j.omtn.2026.103119

Authors: Madison A. Schaefer, Brandon Wilbanks, Irene K. Yan, Alexis M. Sosic, Julia Driscoll, Rory L. Smoot, Tushar Patel, L. James Maher, Shizhen Zhu

Institutions: Mayo Clinic, Mayo Clinic in Florida

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: V Foundation for Cancer Research, National Cancer Institute

Awards: Interplay between low levels of GAS7 expression and MYCN overexpression and its impact on neuroblastoma metastasis, G9001169899

OpenAlex ID: W7214804134

FWCI:

Cites: 22

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Related to: 10