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An epigenetic program dictates MYC amplification dynamics that promote transient, extrachromosomal, and inherited genomic events

Year: 2026
Type: article
DOI: 10.1016/j.molcel.2026.09.032
Authors: Benjamin I. Ferman, Chloe Azadegan, John Santoro, Anushka Udara, Madison A. Lineberger, William Lautert-Dutra, Ethan Sumner, Logan McCullough, Erin O’Donnell, Kashish Chetal, Jade Wilson, Zach Gray, Manna Ahmed, Zhijie Deng, Yan Xiong, H. Umit Kaniskan, Damayanti Chakraborty, Thomas L. Clarke, Sedona E. Murphy, Martin Walsh, Alfonso Bellacosa, Hayan Lee, Jian Jin, Capucine Van Rechem, Michael S. Lawrence, Ruslan I. Sadreyev, Johnathan R. Whetstine
Institutions: Fox Chase Cancer Center, Temple University, Drexel University, Massachusetts General Hospital, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, Harvard University, Stanford University, Broad Institute
Language: English
Open Access status: green
OpenAlex ID: W7214917431
FWCI:
Cites: 134
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Related to: 10