Supplementary material and data for: Use of pumpkin seed (Cucurbita pepo) versus placebo and versus alpha-blockers in the management of benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials
Year: 2026
Type: supplementary-materials
Abstract: Supplementary material, extracted dataset and analysis code for the article Use of pumpkin seed (Cucurbita pepo) versus placebo and versus alpha-blockers in the management of benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials, accepted for publication in Acta Cirúrgica Brasileira (manuscript ACB-2026-0260). Review protocol: PROSPERO CRD420261445031. Supplementary_Material_ACB-2026-0260.pdf — S1, PRISMA 2020 checklist; S2, full search strategies by database; S3, GRADE summary-of-findings table; S4, reports excluded at full-text assessment; S5, PRISMA 2020 flow diagram (text version); S6, supplementary figure legends; S7, assessment of the reports not retrieved; Supplementary Figures S1–S16 (leave-one-out and Baujat diagnostics for the primary outcomes; forest plots and diagnostics for the secondary outcomes). Data_and_code.zip — data.csv (study-level data extracted from the eight included randomized controlled trials), rob2_judgements.csv (Cochrane RoB 2 judgements), psa_sensitivity.csv, analysis_pumpkin_seed_BPH.R (R script, package meta, reproducing every pooled estimate, prediction interval, subgroup test, leave-one-out and Baujat diagnostic and the PSA sensitivity analyses), analysis_output.txt (console output with sessionInfo) and the figure files (PNG).
Authors: Benedicto, Bianca Caroline, Constantinou, Beatriz Taveira, Leite Junior, Amauri Moreira, Orra, Soraya Hussein, Molina, Beatriz Sanches, Almeida, Tayná Pereira Leite de, Navas, Beatriz Brandão da Silva, Sardenberg, Rodrigo Afonso da Silva, Almeida, Fernando Gonçalves de, Maia, Ronaldo Soares, Cruz, José Arnaldo Shiomi da
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7214920239