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Ursodeoxycholic acid enhances cancer radioimmunotherapy by releasing a human-biased FXR-TRIM22-STAT1 immune brake

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Year: 2026
Type: article
Source: Cell Research
DOI: 10.1038/s41422-026-01293-x
Authors: Xinyan Li, Peicheng Jiang, Huan Yin, Zhenyu Huo, Xin Xu, Somaira Nowsheen, Khaled Aziz, Sufei Zheng, Nan Sun, Bin Chen, Zhenkun Lou, Min Deng
Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Molecular Oncology, Mayo Clinic, Cancer Hospital of Chinese Academy of Medical Sciences, Anhui University
Language: English

Topic: Cancer Immunotherapy and Biomarkers
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green
OpenAlex ID: W7214961147
FWCI:
Cites: 49
Cited by:
Related to: 10
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