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Environmentally benign synthesis of functionalized spiro[indoline-3,2′-pyrrole]-2,5′-diones via an aqueous-mediated squaric acid organocatalyzed protocol and their in vitro antimicrobial profiling

Year: 2026

Type: article

Abstract: An efficient, eco-friendly protocol has been developed for the synthesis of functionalized spiro[indoline-3,2′-pyrrole]-2,5′-diones 4(a–r) via a one-pot multicomponent reaction in an aqueous medium using squaric acid as a reusable organocatalyst.

Source: RSC Advances

DOI: 10.1039/d6ra07279h

Authors: Praveen Kumar Atal, Naval Kishor Bairwa, Nisha Jangir, Deepika Choudhary

Institution: University of Rajasthan

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: gold

Estimated APC paid: $1,042