Clinical Experience With the Use of a 675 nm Laser System With a Faster Treatment Strategy for Melasma in Indian Patients
Year: 2026
Type: article
Abstract: Background: Melasma is a commonly acquired hyperpigmentation disorder. Objectives: This is a retrospective, clinical study conducted to evaluate the use of 675 nm wavelength laser treatment in Indian patients affected by facial melasma. Methods: A total of 52 patients with clinically diagnosed melasma were treated with a 675 nm laser system. All participants underwent 4 treatment sessions, each performed at 27 ± 7 day intervals. Patient's pigment reduction and skin homogeneity were assessed with photographic documentation and with the use of the modified Melasma Area and Severity Index at baseline, and 3-month follow-up after the last laser treatment. In addition, patients' satisfaction scores were evaluated. Results: Modified Melasma Area and Severity Index score significantly decreased from 3.8 ± 2.3 at baseline to 2.8 ± 1.7 after treatment. The photographic assessment was consistent with a reduction in pigmentation following treatment. Concerning patient satisfaction scores, 13% of participants reported not being satisfied, 29% were slightly satisfied, 32% were moderately satisfied, and 26% were very satisfied with the overall treatment outcome. There were no major adverse effects reported during the treatment period. Conclusions: The application of the 675 nm laser was associated with short-term improvement to reduce pigmentary symptoms associated with facial melasma in both Indian men and women. However, the retrospective design, absence of a control group, and relatively short follow-up period limit the strength of these findings. Further prospective controlled studies with longer follow-up are needed to confirm efficacy and durability of results.
Institution: El.En. Group (Italy)
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,051
OpenAlex ID: W7215116124