Work

Factors Associated With Candidemia in Hospitalised Patients in Mumbai, India: A Single Centre Retrospective Observational Study

Year: 2026

Type: article

Abstract: IntroductionCandidemia is an important bloodstream infection globally, and there is a variation in species across various regions of the world.Total parenteral nutrition, cancer, surgery, central venous catheterization, and exposure to antibiotics may be potential risk factors for candidemia.We conducted this study to assess the factors associated with Candidemia in hospitalized patients, study the mortality rates and factors associated with mortality, and describe the species in those with candidemia. MethodsThis was a single-center, retrospective, observational study of 139 patients who had candidal growth (cases) on blood culture and 259 patients who did not have any candidal growth (controls) on blood culture (2016-2023) in Mumbai, India.All the blood cultures were processed using the BACT/ALERT ® system (bioMérieux, France), and Candida isolates were identified using the VITEK ® 2 compact system and Matrix-Assisted Laser Desorption/ionization Time-Of-Flight mass spectrometry (MALDI-TOF MS, bioMérieux, France).We used logistic regression models for multivariate analysis, estimated the mortality rates in the study population, and used the Cox proportional hazards models to estimate the hazard ratios for mortality in the study population.

Source: Cureus

DOI: 10.7759/cureus.117338

Authors: Shashikala Shivaprakash, Neetu Biyani, Vasant Nagvekar, Pratiksha Chandorkar, Maninder S Setia

Institution: Sir H.N. Reliance Foundation Hospital and Research Centre

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7215117679