Work

Comprehensive Review of Pancreatic Ductal Adenocarcinoma: Biology, Diagnosis, Treatment, and Future Directions

Year: 2025

Type: article

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, with an overall 5-year survival rate of less than 10%. It represents the seventh leading cause of cancer-related mortality worldwide. The major reasons for poor prognosis include late-stage diagnosis, aggressive tumor biology, and resistance to both systemic and local therapies. This review provides an updated and comprehensive overview of PDAC, including epidemiology, molecular pathogenesis, clinical features, diagnostic modalities, therapeutic approaches, challenges, and future perspectives. The aim is to consolidate current knowledge and highlight areas that may improve early detection and treatment outcomes.

Source: International Journal of Cognitive Neuroscience and Psychology

Author: o’g’li, Jabborov Sherbek Otabek

Institution: Asia International University

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7215264773

FWCI:

Cites: 1

Cited by:

Related to: 10