Year: 2023
Type: article
Abstract: ABSTRACT .Different procedures of PRP preparation can affect the platelet count in PRP. Plateletcount is one of the factors that determines the quality of PRP. This study aimed to describe thenumber of platelets based on variations in anticoagulants and storage time in PRP. This study wasan experimental study with a pre-post test only control group design. PRP was processed from wholeblood from 9 respondents. Whole blood is collected in a tube containing Sodium Citrate, EDTA, andACD-A anticoagulants. Each tube will be processed into PRP through 2 stages of centrifugation.The number of platelets in PRP was counted immediately (0 hour) and counted after 24 hours ofstorage. The results showed that PRP processed using EDTA had the highest platelet count comparedto Sodium Citrate and ACD-A at 0 hour of storage, but decreased at 24 hours of storage. The numberof PRP platelets in ACD-A and Sodium Citrate tubes increased after 24 hours of storage, but the bestplatelet counts were found in ACD-A tubes. The use of anticoagulants in the manufacture of PRP andthe storage time of PRP resulted in varying PRP platelet counts. This study must be carried out furtherin order to determine the concentration of growth factors based on the use of anticoagulants and thestorage time of PRP.
Institution: Akademi Kesehatan John Paul II Pekanbaru
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7215287963