Mutational Analysis of TRAPPC9 IN Non-syndromic Intellectual Disability in Selected Patients
Year: 2026
Type: article
Study design: Observational Study
Abstract: Intellectual incapacity (identity) is a neurodevelopmental circumstance characterized through good sized obstacles in cognitive functioning and adaptive behavior, with onset before the age of 18. It is usually diagnosed in early formative years due to developmental delays in motor, cognitive, and speech abilities, and is generally described by way of an IQ under 70. Identity is classed into syndromic and non-syndromic kinds and further divided into mild, mild, extreme, and profound categories based totally on severity. This takes a look at centered on non-syndromic identification patients, regarding medical evaluation and genetic evaluation. Blood samples have been accrued, and DNA became analyzed the usage of PCR with TRAPPC9 gene primers, followed by gel electrophoresis and sequencing. No mutation became detected in exon 14 of the TRAPPC9 gene, suggesting the want for broader genetic investigations to higher understand and help reduce the prevalence of intellectual incapacity.
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7216333088