Year: 2007
Type: review
Abstract: Introduction: Depressive disorders during youth occur frequently (10%) and are associated with significant comorbidity. ISRS are an effective treatment thatwas prescribed widely across 1990´s. The finding of a relation between the use of antidepressants and an increase of suicidal risk in young people has generated a great controversy in the last years. Objective: To evaluate the risk of the antidepressant use in childhood in relation to the suicidal ideation. Method: We review the current state of research into antidepressant therapy in children and adolescents. Data from randomised controlled trials published in medicaljournals in the last five years were reviewed; we discuss methodologic issues and clinical implications. Results: We have found ten trials that treated about antidepressants and suicidal risk. Four of them suggest that antidepressants protect of suicide, whereas four of them indicated that the risk of suicidal behaviour is increased with antidepressant use. Two studies don´t show significant results. Conclusions: It´s necessary to make specific studies on this subject because the present studies don´t show conclusive results. Nevertheless, depressive disordersmust be treated because their wide frecuency in childhood and their serious comorbidity.
Authors: Marina Aguado, Ana Francés, P. Gracia García
Institution: Hospital Clínico Universitario Lozano Blesa
Language: Spanish
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: diamond
OpenAlex ID: W3168758928