Associations Between Accelerometer-Measured Physical Activity and Incident Type 2 Diabetes: Findings from the UK Biobank Prospective Cohort Study
Year: 2021
Type: article
Study design: Observational Study
Abstract: Background: Very few studies investigating risk of type 2 diabetes (T2D) have directly measured physical activity (PA) via accelerometers. Purpose: To investigate the association of PA, measured by an accelerometer, with T2D incidence. Methods: 40,823 participants from UK Biobank were included in this prospective cohort study. Wrist-worn accelerometers were used to measure total, moderate-to-vigorous (MVPA), moderate (MPA), and vigorous (VPA) PA. All PA domains were categorised into quartiles (Q1 to Q4). Q1 (Lowest quartile) was the reference group. Associations between PA and T2D incidence were analysed using Cox proportional hazard models excluding events in the first two years of follow-up. Results: After excluding the first two years of follow-up, the median follow-up period was 1.8 years (IQR: 1.2; 2.4), with 492 (1.2%) participants developing T2D. Compared to the lowest quartile, the highest quartile was associated with lower risk of T2D (HRtotal PA: 0.29 [95% CI: 0.18 to 0.46], HRMPA: 0.28 [0.17 to 0.44], HRVPA: 0.34 [95% CI: 0.21 to 0.55], HRMVPA: 0.28 [95% CI: 0.17 to 0.45]) after adjusting for socio-demographic and lifestyle factors for women. Conclusions: Accelerometer measured PA is associated with a lower risk of developing T2D. Public health policy should increase focus on increasing PA levels at a population level. Funding: No funding.
Authors: Boonpor, Jirapitcha, Petermann-Rocha, Fanny, Parra-Soto, Solange, Ho, Frederick, Celis-Morales, Carlos, Gray, Stuart
Language: English
Topic: Physical Activity and Health
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W6904925076