Year: 2023
Type: article
Study design: Observational Study
Abstract: Among the symptoms of COVID-19 prognostic value are fever, diarrhea, abdominal pain and dyspnea; while the signs can be pulmonary rales, arterial hypotension, hypoxemia, tachypnea and tachycardia. Also the patient's phenotype may be associated with the risk of death.The work is proposed as an objectiveto evaluate the ability of a model to predict the risk of dying in patients with COVID-19, based on clinical manifestations and phenotypes. An analytical observational cohort study was carried out in patients with COVID-19 treated in the services of the hospital "COVID-19", of the general provincial hospital Carlos Manuel de Céspedes of Bayamo municipality, Granma province, from January 1, 2020 to December 31, 2022.The Cox proportional model proved that the variable with the highest association with the risk of dying from covid-19 was classifying in phenotype 5 (Hazard ratio= 8.09; 95 % CI= 3.45-18.92; p = 0.000) followed by classifying in phenotype 4 (Hazard ratio= 2.21; 95 % CI= 1.84-5.79; p = 0.008) and blood pressure ≤ 90/60 mmHg (Hazard ratio= 1.49; 95 % CI= 1.26-2.63; p =0.008). None of the symptoms showed independent association with the prognosis of death due to COVID-19.The association with the risk of dying from COVID-19 and phenotype 4 and 5 was demonstrated, as well as the bioparameters of tissue hypoperfusion. The model obtained can be used to predict the evolution of individuals with the aforementioned disease.
Source: Multimed
Language: Spanish
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7219409536