Work

Design, Synthesis, and Anti-Inflammatory Activity Evaluation of Novel thieno[2,3- d ]Pyrimidin-4(3 H )-One-Based NLRP3 Inflammasome Inhibitors

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c02162

Authors: Yuqi Jiang, Simin Sun, Jinyu Liu, Jiayue Huang, Huimin Wang, Tongqiang Xu, Leyan Wang, Zhendi Shi, Xiaoyang Li

Institutions: Qingdao National Laboratory for Marine Science and Technology, Marine Biomedical Research Institute of Qingdao, Ocean University of China

Language: English

Topic: Inflammasome and immune disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Ocean University of China, Natural Science Foundation of Shandong Province, Natural Science Foundation of Qingdao, Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China

Awards: G251534359, G2904763380, G9000855847

OpenAlex ID: W7219625387

FWCI:

Cites: 68

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