Noxas pre- peri- y posnatales como signos de alerta en niños con trastorno del espectro autista
Year: 2026
Type: article
Study design: Observational Study
Abstract: Introduction: Autism spectrum disorders encompass a wide range of clinical presentations, etiologies, and symptom severities. Research in this area has expanded in recent years; however, diagnosis remains delayed. Identifying early warning signs can facilitate diagnosis. Objective: To identify pre-, peri-, and postnatal noxious factors present in children with autism spectrum disorder. Methods: An observational, descriptive, retrospective study was conducted on 51 children with autism spectrum disorder in the province of Sancti Spíritus, focusing on identifying noxious factors present before, during, and one year after birth. Results: The 5-to-9-year-old age group predominated (43.1%), and males accounted for 84.3% of the subjects. Almost all patients presented with some type of noxious factor, with 94.1% of these being postnatal. Maternal diseases and medication use represented a significant proportion, with obesity, hypertension, and mental disorders being particularly notable. 76.5% of the children were born via cesarean section; the most significant postnatal noxious factors observed were sleep disorders (70.6%), epilepsy (56.9%), and language disorders (80.4%). Conclusions: The study group presented significant pre-, peri-, and postnatal noxious factors that are easily observable during pediatric follow-up and indicate a deviation from neurotypical development. Almost all cases presented with some type of noxious factor; maternal diseases and medication use were the most frequent during the prenatal period.
Institution: Universidad de Ciencias Médicas de Sancti Spíritus
Language: Spanish
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W7220273098