Global, Regional, and National Burden of Heart Failure, 1990-2023: A Systematic Analysis for the Global Burden of Disease Study 2023.
Year: 2026
Type: article
Study design: Observational Study
Abstract: Importance: Heart failure (HF) is a common condition with substantial geographical variation in its prevalence and underlying etiologies. Consistent and comparable data on the burden of HF within populations are needed to inform health system priorities. Objective: To estimate the global burden of HF. Design, Setting, and Participants: This cross-sectional study estimates disease burden using Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) methodologies to integrate multiple information sources. Data come from 204 countries and territories from 1990 to 2023 representing the global population with prevalent HF. Exposure: HF and underlying etiologies. Main Outcomes and Measures: Estimates with 95% uncertainty intervals (UIs) for the prevalence and years lived with disability (YLDs) for HF by age, sex, location, year, and underlying etiology. Results: Globally, there were 56.0 million (95% UI, 49.9-62.2 million) estimated cases of HF in 2023. The estimated prevalence of HF generally increased with age for all locations. While ischemic heart disease and hypertensive heart disease were the 2 most common etiologies globally among older adults, there was substantial variation in etiological pattern by location and age. Congenital heart anomalies and rheumatic heart disease (RHD) were common etiologies in children and young adults, while the proportion of HF due to alcohol use peaked in middle adulthood. Location-specific estimates highlighted regions with higher burden of HF due to specific etiologies, including RHD (south Asia, east Asia, Oceania, southeast Asia, central sub-Saharan Africa, eastern sub-Saharan Africa, southern sub-Saharan Africa, and western sub-Saharan Africa), alcohol use (eastern Europe, Australasia, the Caribbean, and central Europe), and Chagas disease (southern, Andean, tropical, and central Latin America). Conclusions and Relevance: Heart failure is a significant global public health burden, and the impact is likely to increase as populations age. However, most HF etiologies can be prevented by interventions that reduce exposure to modifiable risk factors, such as elevated blood pressure, excessive alcohol consumption, and tobacco use. Etiology- and location-specific estimates can provide necessary information for public health officials to determine how best to prioritize interventions to reduce HF disease burden.
Authors: Catherine O Johnson, Madineh Abbasi, Mitra Abbasifard, Hedayat Abbastabar, Samar Abd ElHafeez, Nadin M Abdel Razeq, Ahmed Abdelrahman Abdelgalil, Ali Abdolizadeh, Meriem Abdoun, Mostafa Abdrabou, Auwal Abdullahi, Tesfaye Birhanu Abebe, Asrat Agalu Abejew, Olifan Zewdie Abil, Olumide Abiodun, Richard Gyan Aboagye, Shady Abohashem, Mostafa A Aboouf, Moaz Elsayed Abouelmagd, Mohamed Abouzid, Dmitry Abramov, Dariush Abtahi, Fuad Hamdi Abuadas, Eman Abu-Gharbieh, Ahmad Y Abuhelwa, Dina Abushanab, Lisa C Adams, Isaac Yeboah Addo, Kamoru Ademola Adedokun, Oluwatobi Emmanuel Adegbile, Nurudeen A Adegoke, Olumide Thomas Adeleke, Makinde Adebayo Adeniyi, Miracle Ayomikun Adesina, Ridwan Olamilekan Adesola, Kishor Adhikari, Molalign Aligaz Adisu, Prince Owusu Adoma, Clifford Afoakwah, Ebenezer Afrifa-Yamoah, Muhammad Sohail Afzal, Mohammad Aghaali, Feleke Doyore Agide, Percival Delali Agordoh, Cesar Agostinis Sobrinho, Piyush Agrawal, Williams Agyemang-Duah, Danish Ahmad, Muayyad Ahmad, Saheem Ahmad, Sajjad Ahmad, Suhaib Ahmad, Waqas Ahmad, Ali Ahmadi, Sepideh Ahmadi, Sarina Ahmadian, Koohyar Ahmadzadeh, Ayman Ahmed, Gasha Salih Ahmed, Muktar Beshir Ahmed, Mushood Ahmed, Shahzaib Ahmed, Syed Anees Ahmed, Marjan Ajami, Aanuoluwatimileyin Ibukunoluwa Ajayi, Roland Eghoghosoa Akhigbe, Muhammad Nadeem Akhtar, Salah Thabit Al Awaidy, Tariq Al Bahhawi, Syed Mahfuz Al Hasan, Mohammad Khaled Al Nawayseh, Yazan Al Thaher, Omar Ali Mohammed Al Zaabi, Mohammad Ahmmad Mahmoud Al Zoubi, Fares Alahdab, Mohammad M Al-Ahmad, Samer O Alalalmeh, Mohammad Khursheed Alam, Rabail Alam, Fahad Alanezi, Turki Alanzi, Fahmi Y Al-Ashwal, Rashid Alavi, Mohammed Sad ALBashtawy, Belal Aldabbour, Astefanos Al-Dalakta, Khalifah A Aldawsari, Nader Al-Dewik, Shereen M Aleidi, Ali M Alfalki, Abdelazeem Algammal, Mohammed Algethami, Khalid Alhabib, Fadwa Naji Alhalaiqa, Fahad A Alhumaydhi, Irfan Ali, Mohammad Daud Ali, Mohammed Usman Ali, Rafat Ali, Syed Shujait Ali, Syed Yusuf Ali, Sheikh Mohammad Alif, Esubalew Muluneh Aligaz, Mina Alimohammadi, Mamman Aliyu Na’uzo, Samah W Al-Jabi, Moath Saleh Aljohani, Syed Mohamed Aljunid, Sameer Abdulmalik Alkubati, François Alla, Khaled S Allemailem, Mohammed Z Allouh, Wesam Taher Almagharbeh, Wael Abdulrahman Almahmeed, Sabah Al-Marwani, Joseph Almazan, Mohammad Minwer Alnaeem, Hasan Yaser Alniss, Mahmoud A Alomari, Mohammad R Alosta, Mohammad Al-Qudah, Ahmad R Al-Qudimat, Ahmad Alrawashdeh, Rami H Al-Rifai, Intima Alrimawi, Mustafa Alsaadi, Najim Z Alshahrani, Awais Altaf, Obieda Altobaishat, Diala Altwalbeh, Nelson Alvis-Guzman, Yaser Mohammed Al-Worafi, Hany Aly, Mohammad S Alyahya, Abdulmohsen Hamdan Al-Zalabani, Abdallah Alzoubi, Karem H Alzoubi, Adel Sharaf Al-Zubairi, Walid Adnan Al-Zyoud, Saeed Amini, Anandhi Deva Amirtharaj, Enrico Ammirati, Hubert Amu, Ganiyu Adeniyi Amusa, Filippos Anagnostakis, Roshan Ananda, Catalina Liliana Andrei, Song Peng Ang, Abhishek Anil, Sanvithi Anjanappa, Reindolf Anokye, Boluwatife Stephen Anuoluwa, Iyadunni Adesola Anuoluwa, Saeid Anvari, Anayochukwu Edward Anyasodor, Geminn Louis Carace Apostol, Hossein Arabi, Jalal Arabloo, Aleksandr Aravkin, Demelash Areda, Abdulfatai Aremu, Jorge Arias de la Torre, Timur Aripov, Ghazal Arjmand, Johan Ärnlöv, Nurila Aryntayeva, Evans Atiah Asamane, Guido Ascione, Syed Mohammed Basheeruddin Asdaq, Saad Ashraf, Tahira Ashraf, Bernard Kwadwo Yeboah Asiamah-Asare, Muhammad Shahzad Aslam, Anil Raj Assariparambil, Ömer Ataç, Seyyed Shamsadin Athari, Prince Atorkey, Avinash Aujayeb, Zaw Zaw Aung, Khursheed Aurangzeb, Usman Ayub Awan, Kemal Lemnuro Awol, Adedapo Wasiu Awotidebe, Ahmad Ayed, AKM Azad, Arian Azadnia, Hiva Azami, Alireza Azarboo, Mehrnaz Azarian, Mohd Yusmaidie Aziz, Sadat Abdulla Aziz, Domenico Azzolino, Abraham Samuel Babu, Raham Bacha, Muhammad Badar, Nasser Bagheri, Khlood Baghlaf, Atif Amin Baig, Mohamad Amin Bakhshali, Senthilkumar Balakrishnan, Ovidiu Constantin Baltatu, Ruwanthi Panchali Bandara, Biswajit Banik, Hiba Jawdat Barqawi, Zarrin Basharat, Shahid Bashir, Azadeh Bashiri, Afisu Basiru, Mohammad-Mahdi Bastan, Nour Batarseh, Armel Landry Batchi-Bouyou, Shazia Batool, Narasimha M Beeraka, Babak Behnam, Bekalu Mekonen Belay, Samiun Nazrin Bente Kamal Tune, Kenechukwu Chijioke Ben-Umeh, Abiye Assefa Berihun, Devidas S Bhagat, Nikha Bhardwaj, Pankaj Bhardwaj, Sonu Bhaskar, Priyadarshini Bhattacharjee, Sudip Bhattacharya, Gurjit Kaur Bhatti, Md Mehedi Hasan Bhuiyan, Tia Bimal, Ahmad Naoras Bitar, Bruno Bizzozero-Peroni, Lucimere Bohn, Mina Borran, Alejandro Botero Carvajal, Souad Bouaoud, Christopher Boxe, Luisa C Brant, Raffaele Bugiardini, Linh Phuong Bui, Norma B Bulamu, Felix Busch, Yasser Khalil Bustanji, Luciana Aparecida Campos, Yu Cao, Zhong Cao, Angelo Capodici, Felix Carvalho, Aditya Chakraborty, Chiranjib Chakraborty, Sandip Chakraborty, Jeffrey Shi Kai Chan, Baskaran Chandrasekaran, Vijay Kumar Chattu, Lam Duc Chau, Anis Ahmad Chaudhary, Asad Ali Ahmed Cheema, An-Tian Chen, Hana Chen, Haowei Chen, Meng Xuan Chen, Xing Chen, Nicholas Chew, Gerald Chi, Patrick R Ching, Bryan Chong, Karleen Chong, Deepti Chopra, Hitesh Chopra, Sonali G Choudhari, Enayet Karim Chowdhury, Rajiv Chowdhury, Jinky Marie Tuliao Chua, Sheng-Chia Chung, Sunghyun Chung, Arrigo Francesco Giuseppe Cicero, Mariana Corda, Claudia Cosma, Vera Marisa Costa, Natália Cruz-Martins, Omid Dadras, Jiahui Dai, Xiaochen Dai, Mayank Dalakoti, Albertino Damasceno, Emanuele D’Amico, Lucio D’Anna, Samuel Demissie Darcho, Dimash Davletov, Tadesse Asmamaw Dejenie, Ivan Delgado-Enciso, Ismail Dergaa, Emina Dervišević, Hardik Dineshbhai Desai, Vinoth Gnana Chellaiyan Devanbu, Arkadeep Dhali, Amol S Dhane, Bibha Dhungel, Marcello Di Pumpo, Diana Dias da Silva, Huynh Phuong Thao Do, Thanh Chi Do, Sushil Dohare, Fariba Dorostkar, Ojas Prakashbhai Doshi, Paulo Magno Martins Dourado, Emeka Dumbili, Andre Rodrigues Duraes, Senbagam Balakrishnan Duraisamy, Siddhartha Dutta, Subhajit Dutta, Abdel Rahman E’mar, Cynthia Edeh, David Jan Edvardsson, Debela Ejeta, Michael Ekholuenetale, Rabie Adel El Arab, Iman El Sayed, Mohamed Ahmed Eladl, Aya Elalfy, Islam Y Elgendy, Muhammed Elhadi, Waseem El-Huneidi, Sherif Elkhanishy, Omar Abdelsadek Abdou Elmeligy, Mohamed A Elmonem, Adel B Elmoselhi, Mohamed Hassan Elnaem, Abdelgawad Salah Eltahawy, Theophilus I Emeto, Fahima Nasrin Eva, Natalia Fabin, Heidar Fadavian, Adeniyi Francis Fagbamigbe, Ildar Fakhradiyev, Mohammad Fareed, Aisha Farhana, Wisam Fawzi Al-Juhyiish, Timur Fazylov, Gelana Fekadu, Ginenus Fekadu, Rodrigo Fernandez-Jimenez, Pietro Ferrara, Nuno Ferreira, Florian Fischer, Luisa Sorio Flor, Federica Fogacci, Carla Fornari, Célia Fortuna Rodrigues, Matteo Foschi, Abdelrahman Gamil Gad, Abduzhappar Gaipov, Ezhilkugan Ganessane, Shivaprakash Gangachannaiah, Anirban Ganguli, Dingwei Gao, Fernando Barroga Garcia, Chandi Garg, Jacopo Garlasco, Bamba Gaye, Mesfin Gebrehiwot, Ali Gerami Matin, Lemma Getacher, Genanew Kassie Getahun, Kalab Yigermal Gete, Mustafa Ghaderzadeh, Kazem Ghaffari, Amir Ghaffari Jolfayi, Roya Ghafoury, Arin Ghamkhar, Lobna Gharaibeh, Mohammadreza Ghasemi, Ahmad Ghashghaee, Ramy Mohamed Ghazy, Nermin Mahmoud Mohammed Ghith, Sama Ghoba, Artyom Gil, Syed Abdullah Gilani, Richard Frank Gillum, Soliyana Gizachew, Laszlo Göbölös, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Melika Golmohammadi, Yitayal Ayalew Goshu, Alessandra C Goulart, Habtamu Alganeh Guadie, Avirup Guha, Damitha Asanga Gunawardane, Lalit Gupta, Mohak Gupta, Rajeev Gupta, Saptorshi Gupta, Roberth Steven Gutiérrez-Murillo, Eduardo Guzmán-Muñoz, Najah R Hadi, Arian Haghtalab, Abdulsalam M Halboup, Pritam Halder, Sobia Ahsan Halim, Nadia M Hamdy, Mohamed Hamed, Hossein Hamidi, Samer Hamidi, Erin B Hamilton, Asif Hanif, Nasrin Hanifi, Fahad Hanna, Mohd Anul Haq, Obaid Imtiyazul Haque, Ahmed Ibrahim Hasaballah, Faizul Hasan, Md Kamrul Hasan, SM Mahmudul Hasan, Hamidreza Hasani, Mohammad Hashem Hashempur, Ibrahim Nagmeldin Hassan, Ikrama Ibrahim Hassan, Md Imtaiyaz Hassan, Muhammad Hassan, Nageeb Abdul Galil Hassan, Shoaib Hassan, Rasmus J Havmoeller, Simon Iain Hay, Ahmad Hayatu, Wen-Qiang He, Golnaz Heidari, Mohammad Heidari, Zaw Myo Hein, Sumudu Avanthi Hewage, Kamal Hezam, Yuta Hiraike, Mai Hoang, Ramesh Holla, Alamgir Hossain, Md Sabbir Hossain, Syed Billal Hossain, Mehdi Hosseinzadeh, Mihaela Hostiuc, Junjie Huang, Kiavash Hushmandi, Dursa Hussein, Thuan Nguyen Huynh, Bing-Fang Hwang, Segun Emmanuel Ibitoye, Fatma Magdi Ibrahim, Rasha Kadri Ibrahim, Anel Ibrayeva, Aqsa Ikram, Irena Ilic, Milena Ilic, Salim Ilyasu, Lucius Chidiebere Imoh, Danish Iqbal, Muhammad Iqhrammullah, Bilal Irfan, Md Rabiul Islam, Yerlan Ismoldayev, Hiroyasu Iso, Masao Iwagami, Chidozie Declan Iwu, Chinwe Iwu-Jaja, Oshozimhede E Iyalomhe, Shadi Izadidehkordi, Juan S Izquierdo-Condoy, Jalil Jaafari, Jaison Jacob, Ali Jadidi, Ali Jafari-Khounigh, Vennila Jaganathan, Haitham Jahrami, Vikash Jaiswal, Reza Jalilzadeh Yengejeh, Armaan Jamal, Jazlan Jamaluddin, Safayet Jamil, Talha Jawaid, Yovanthi Anurangi Jayasinghe, Jayakumar Jeganathan, Seogsong Jeong, Zixiang Ji, Jost B Jonas, Tamas Joo, Jobin Jose, Jobinse Jose, Akaninyene Paul Joseph, Mickael Antoine Joseph, Krupal J Joshi, Charity Ehimwenma Joshua, Farahnaz Joukar, Jacek Jerzy Jozwiak, Sang-Hyuk Jung, Malik Juweid, Billingsley Kaambwa, Dler Hussein Kadir, Farima Kahe, Ashish Kumar Kakkar, Khalil Kalavani, Sanjay Kalra, Ramat Toyin Kamorudeen, Oleksandr Kamyshnyi, Jiseung Kang
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7220369312