Work

Hospital-at-Home management of Wickerhamiella pararugosa candidemia and treatment with rezafungin: A case report

Year: 2026

Type: article

Abstract: ABSTRACT Wickerhamiella pararugosa , a rare cause of bloodstream infection, was identified in an 87-year-old woman admitted to a Hospital-at-Home unit for a complicated urinary tract infection, without a central venous catheter. Empirical micafungin was switched to rezafungin, a long-acting echinocandin, enabling HaH-based completion of therapy. Work-up revealed Takotsubo syndrome, managed without disrupting antifungal treatment. This is the first reported HaH management of this species and the first use of rezafungin for W. pararugosa infection.

Source: Medical Mycology Case Reports

DOI: 10.1016/j.mmcr.2026.100827

Authors: Inigo Vázquez Gomara, Javier Bernardo Perez-Serrano, Ma Auxiliadora Semiglia Chong, Lidia Vilches-Miguel, Diego Real de Asua Cruzat, Pablo Rodriguez-Cortes

Institutions: Hospital Universitario de La Princesa, Universidad Autónoma de Madrid

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $650