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4646 A two-step organoid-based screen identifies MDM2 inhibition as a senolytic strategy to ameliorate radiation-induced salivary gland dysfunction

Year: 2026

Type: article

Source: Radiotherapy and Oncology

DOI: 10.1016/s0167-8140(26)03951-4

Authors: Abel Soto-Gamez, Yi Wu, Eline Hageman, Uilke Brouwer, Davide Cinat, Arjan Vissink, Marco Demaria, Lara Barazzuol, Sarah Pringle, Rob P Coppes

Language: English

Topic: Telomeres, Telomerase, and Senescence

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7220429595

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