Work

Salmon bone-derived chondroitin sulfate nanogels for controlled delivery of curcumin: release behavior, structural characteristics and anti-inflammatory efficacy

Year: 2026

Type: article

Abstract: = 0.711). Furthermore, in LPS-stimulated RAW 264.7 macrophages, the CS-Cur nanogels showed significantly enhanced anti-inflammatory efficacy and high biocompatibility compared to free curcumin. These findings highlight salmon bone-derived CS as a sustainable, high-performance matrix for hydrophobic drug delivery, providing new insights into the role of cargo-induced structural organization in regulating therapeutic release and biological performance.

Source: RSC Advances

DOI: 10.1039/d6ra06378k

Authors: Quang Van Ngo, Nguyen Chi Nguyen, Hong Thi Pham, Cuong Duc Ho, Thu Thi Minh Quach, Thuy Thi Thu Thanh

Institutions: Viện Hóa học, Vietnam Academy of Science and Technology, Trường Đại học Khoa học và Công nghệ Hà Nội, Hanoi University of Science and Technology

Language: English

Topic: Advanced Drug Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042