Unlocking the molecular mechanisms of bamboo-based remediation of hazardous contaminants: macromolecular interactions, transport pathways, and predictive approaches
Year: 2026
Type: review
Abstract: Bamboo presents an unusual combination of rapid biomass production and diverse molecular mechanisms for capturing, transforming, and sequestering hazardous contaminants. However, the existing investigations have predominantly focused on bulk removal efficiencies and tissue-level accumulation profiles, whereas the molecular determinants governing these processes remain critically underexplored. This review systematically synthesizes the structure-function relationships of key bamboo-derived macromolecules including cellulose, hemicellulose, lignin, membrane transport proteins such as heavy metal ATPases (HMAs), ATP-binding cassette (ABC) transporters, natural resistance-associated macrophage proteins (NRAMPs), and zinc-regulated/iron-regulated transporter-like proteins (ZIPs), as well as oxidative enzymes such as laccases and peroxidases. Specific emphasis is placed on the molecular features that drive contaminant adsorption, transport, sequestration, and degradation. Particular attention is given to surface functional groups, aromatic domains, conserved transporter motifs, and catalytic metal centers. A critical appraisal of the current literature reveals substantial knowledge gaps, particularly in molecular-weight distributions, three-dimensional conformational states, binding affinities, and direct physicochemical interactions between bamboo-derived macromolecules and hazardous pollutants. To address these limitations, we propose an integrative framework combining proteomics, AI-assisted structure prediction, molecular docking, molecular dynamics (MD) simulations, and quantitative binding assays to uncover the molecular basis of bamboo-pollutant interactions. Future breakthroughs will require the synergistic integration of rigorous structural characterization and direct interaction studies to move from descriptive associations toward predictive structure-function relationships. By consolidating dispersed knowledge and outlining prioritized research agendas, this review furnishes a conceptual framework to advance bamboo-based remediation from descriptive observational studies toward predictive, mechanism-driven strategies for hazardous contaminant management and environmental risk reduction.
Source: Frontiers in Plant Science
Institutions: Sichuan Agricultural University, University of Narowal
Language: English
Subfield: Water Science and Technology
Field: Environmental Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7220468842