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Genetics and Epigenetics of Chronic Allograft Dysfunction in Kidney Transplants

Year: 2016

Type: article

Abstract: Chronic allograft dysfunction is the most common cause of allograft lost. Chronic allograft dysfunction happens as a result of complex interactions at the molecular and cellular levels. Genetic and environmental factors both influence the evolution and progression of the chronic allograft dysfunction. Epigenetic modification could be considered as a therapeutically modifiable element to pause the fibrosis process through novel strategies. In this review, the PubMed database was searched for English-language articles on these new areas.

Source: Iranian Journal of Kidney Diseases

Authors: Zununi Vahed, Sepideh, Samadi, Nasser, Mostafidi, Elmira, Ardalan, Mohammad Reza, Omidi, Yadollah

Institutions: Tabriz University of Medical Sciences, Imam Reza Hospital, Research Center for Pharmaceutical Nanotechnology

Language: English

Topic: Renal Transplantation Outcomes and Treatments

Subfield: Transplantation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7220514827

FWCI:

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