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Reducing peripheral intravenous catheter–related phlebitis: a multi-centre multi-component toolkit implementation study

Year: 2026
Type: article
Study design: Clinical Trial
Abstract: Structured summary Background Phlebitis is a frequent complication of peripheral intravenous catheters, leading to patient discomfort, inflammation, antibiotic use, and prolonged hospitalization. A multicomponent Phlebitis Prevention Toolkit was developed to support healthcare workers in reducing phlebitis incidence. Methods The Toolkit - comprising an infographic, digital newsletter, nurse training, and a standardized protocol - was implemented in four Dutch hospitals (2024–2025). Each hospital prospectively collected data on catheter characteristics, insertion site observations, and phlebitis occurrence during a two-month pre-implementation period and a 2.5-month post-implementation period. The primary outcome was the change in phlebitis incidence. Results Phlebitis incidence decreased from 7.3% (84/1144) to 4.9% (48/976) ( P = 0.02). A significant reduction was observed in one site, while site-level changes varied across hospitals. Phlebitis was more frequent when insertion sites were not visible (10.4% vs. 5.4%; RR 1.92; P < 0.001) and when dressings were soiled, wet, or loose (20.4% vs. 3.2%; RR 6.45; P < 0.001). Longer catheter dwell time was associated with progressively higher phlebitis incidence. Conclusions Implementation of a simple, multicomponent Toolkit was associated with a reduction in phlebitis incidence and highlights the importance of insertion site visibility, dressing integrity, and timely catheter removal for safer peripheral intravenous care.
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,500
OpenAlex ID: W7220699926
FWCI:
Cites: 4
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Related to: 10