Work

Development and characterization of [ 99m Tc]Tc-lornoxicam as a potential COX-assisted radiopharmaceutical for inflammation imaging

Year: 2026

Type: article

Abstract: Tc]Tc-lornoxicam demonstrated a high labeling yield, satisfactory stability, moderate lipophilicity, and preferential inflammation-associated localization. These findings support the potential of the radiotracer as a COX-targeted radiopharmaceutical for inflammation imaging, although further molecular investigations are warranted to establish its COX-specific targeting mechanism.

Source: RSC Advances

DOI: 10.1039/d6ra08252a

Authors: Atifa Batool, Tania Jabar, Syeda Minahal Fatima, Syed Muhammad Waji-Ul-Hassan, Nayyar Rubab, Hafiz Kush Naseeb Ahmad, Mohamed Fawzy Ramadan, Nouf Aldawood, Tahani O. Alkahtani, Abdulaziz A. Alshihri, Nadeem Ahmad Lodhi, Syed Ali Raza Naqvi

Institutions: Government College University, Faisalabad, CMH Multan Institute of Medical Sciences, Allama Iqbal Medical College, Umm al-Qura University, Princess Nourah bint Abdulrahman University, King Khalid University, Pakistan Institute of Nuclear Science and Technology

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

OpenAlex ID: W7220839332

FWCI:

Cites: 43

Cited by:

Related to: 10